ILF2 Antibody - C-terminal region : HRP (ARP35731_T100-HRP)

Catalog No: ARP35731_T100-HRP

Size:100ul

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Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ILF2
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
• Peptide Sequence: Synthetic peptide located within the following region: HGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ILF2 (ARP35731_T100-HRP) antibody is Catalog # AAP35731 (Previous Catalog # AAPP06977)
• Sample Type Confirmation:

  ILF2 is supported by BioGPS gene expression data to be expressed in MCF7

• Reference: Shin,H.J., et al., (2002) Arch. Virol. 147 (3), 471-491
• Publications:

  Jiang, D., Zhou, Y., Moxley, R. A. & Jarrett, H. W. Purification and identification of positive regulators binding to a novel element in the c-Jun promoter. Biochemistry 47, 9318-34 (2008). WB, Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish 18690718

  Yamauchi, T. et al. Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression. Biochem. Biophys. Res. Commun. 425, 711-6 (2012). WB, ICC/IF, Rat, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish 22842455

Target Info

• Gene Symbol: ILF2
• Gene Full Name: Interleukin enhancer binding factor 2, 45kDa
• Alias Symbols: NF45, PRO3063
• NCBI Gene Id: 3608
• Protein Name: Interleukin enhancer-binding factor 2
• Description of Target: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of the ILF2 gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.
• Uniprot ID: Q12905
• Protein Accession #: NP_004506
• Nucleotide Accession #: NM_004515
• Protein Size (# AA): 390
• Molecular Weight: 43kDa
• Protein Interactions: CCNDBP1; HUWE1; UBC; EEF1G; AURKA; SUMO2; SUMO3; STAU1; IVNS1ABP; RPA1; SMURF2; RPA3; RPA2; ERG; EZH2; BMI1; SUZ12; EED; rev; HNRNPU; FKBP3; DHX9; DDX1; ABCF1; C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; EIF2B2; EIF2B3; YBX3; RFC4; PTBP1; YBX1; NMT1; MR