Catalog No: ARP59084_P050
Price: $0.00
SKU
ARP59084_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-IL7R (ARP59084_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Dog, Horse
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human IL7R
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 92%; Horse: 83%; Human: 100%
Peptide SequenceSynthetic peptide located within the following region: ESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCP
Concentration0.5 mg/ml
Blocking PeptideFor anti-IL7R (ARP59084_P050) antibody is Catalog # AAP59084 (Previous Catalog # AAPP45764)
Subunitalpha
Gene SymbolIL7R
Gene Full NameInterleukin 7 receptor
Alias SymbolsILRA, CD127, IL7RA, CDW127, IL-7R-alpha
NCBI Gene Id3575
Protein NameInterleukin-7 receptor subunit alpha
Description of TargetThe protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
Uniprot IDP16871
Protein Accession #NP_002176
Nucleotide Accession #NM_002185
Protein Size (# AA)459
Molecular Weight49kDa
Protein InteractionsKIT; JAK3; SNRPG; SNRPD3; SNRPD2; SNRPD1; SNRPB; SNRPA; SNRNP70; SRSF3; SAFB; RPS20; RPS3; RPL31; RPL29; RPL30; RPL22; RPL18; RPL15; RPL8; RPL7; RPL6; RBM3; PURB; PURA; PTMA; PTBP1; EIF2AK2; YBX1; NONO; NCL; MAP4; RPSA; ILF3; ILF2; HNRNPU; HNRNPL; HNRNPH3
  1. What is the species homology for "IL7R Antibody - middle region (ARP59084_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Dog, Horse".

  2. How long will it take to receive "IL7R Antibody - middle region (ARP59084_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "IL7R Antibody - middle region (ARP59084_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "IL7R Antibody - middle region (ARP59084_P050)"?

    This target may also be called "ILRA, CD127, IL7RA, CDW127, IL-7R-alpha" in publications.

  5. What is the shipping cost for "IL7R Antibody - middle region (ARP59084_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "IL7R Antibody - middle region (ARP59084_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "IL7R Antibody - middle region (ARP59084_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "IL7R Antibody - middle region (ARP59084_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "IL7R"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IL7R"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IL7R"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IL7R"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IL7R"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IL7R"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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