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OATA00070
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IL7R Antibody : APC (OATA00070)

Catalog#: OATA00070
Domestic: within 1 week delivery | International: 1 week
More Information
Tested Species Reactivity Mouse
Product Format Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
Clonality Monoclonal
Clone A7R34
Isotype Rat IgG2a, kappa
Host Rat
Conjugation APC: Allophycocyanin
Application FC
:: Excitation Laser: Red (633-640 nm)
:: Emmision: 660 nm
Reconstitution and Storage 2-8C protected from light
Datasheets/Manuals Printable datasheet for OATA00070
Specificity CD127 (IL-7Ra)
Application Info This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
Target Reference

Thaventhiran JED, Hoffmann A, Magiera L, de la Roche M, Lingel H, Brunner-Weinzierl M, and Fearon DT. 2012. Proc. Natl. Acad. Sci. 10.1073. (Flow cytometry).

Jin J, Goldschneider I, and Lai L. 2011. J. Immunol. 186: 1915-1922. (in vivo activation)

Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, and Mebius RE. 2009. J. Immunol. 182(9): 5439-5445. (Immunofluorescence microscopy - frozen tissue)

Leithauser F, Meinhardt-Krajina T, Fink K, Wotschke B, Moller P and Reimann J. 2006. Am. J. Pathol. 168(6): 1898-1909. (Immunohistochemistry - frozen tissue)

Seddon B and Zamoyska R. 2002. J. Immunol. 169: 2997-3005. (in vivo activation)

Sudo T, Nishikawa S, Ohno N, Akiyama N, Tamakoshi M, Yoshida H and Nishikawa S-I. 1993. Proc. Natl. Acad. Sci. 90: 9125-9129. (in vitro and in vivo blocking; Immunoprecipitation)

Gene Symbol IL7R
Official Gene Full Name interleukin 7 receptor
Alias Symbols CD127, IL-7Ralpha
NCBI Gene Id 16172
Protein Name interleukin-7 receptor subunit alpha
Description of Target Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.
Swissprot Id P16872
Protein Accession # NP_032398.3
Nucleotide Accession # NM_008372.4
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express IL7R.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express IL7R.
  1. What is the species homology for "IL7R Antibody : APC (OATA00070)"?

    The tested species reactivity for this item is "Mouse". This antibody is predicted to have homology to "".

  2. How long will it take to receive "IL7R Antibody : APC (OATA00070)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "IL7R Antibody : APC (OATA00070)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "IL7R Antibody : APC (OATA00070)"?

    This target may also be called "CD127, IL-7Ralpha" in publications.

  5. What is the shipping cost for "IL7R Antibody : APC (OATA00070)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "IL7R Antibody : APC (OATA00070)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "IL7R Antibody : APC (OATA00070)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "IL7R Antibody : APC (OATA00070)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "IL7R"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IL7R"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IL7R"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IL7R"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IL7R"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IL7R"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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