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IL6R Antibody (OASA01186)

0.1 mg
$385.00
In Stock
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Gene Symbol:
IL6R
NCBI Gene Id:
3570
Protein Name:
Interleukin-6 receptor subunit alpha
Swissprot Id:
P08887
Protein Accession #:
NP_000556.1
Alias Symbols:
CD126, IL6RA, IL-6R-1, MGC104991, IL-6R-alpha, IL6R
Replacement Item:
This antibody may replace item sc-13947 from Santa Cruz Biotechnology.
Description of Target:
MOUSE ANTI HUMAN CD126 (IL-6R)
Protein Size (# AA):
468
Host:
Mouse
Clonality:
Monoclonal
Application:
IHC-AFF, ELISA, FC, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express IL6R.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express IL6R.
Immunogen:
The immunogen for anti-IL6R antibody: cHO cells transfected with cDNA of the IL-6 receptor
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-IL6R antibody - OASA01186
Specificity:
CD126
Clone:
B-R6
Isotype:
IgG1
Application Info:
Flow Cytometry:    1/50
Additional Information:
Fusion Partners: Spleen cellls from immunised BALB/c (Iffa Credo) mice were fused with the X63/Ag.8653 mouse myeloma cell line.
:::
Preparation: Purified IgG prepared by ion exchange chromatography
Preservative Stabilisers: 0.09% - Sodium Azide
:::
Approx Protein Conc: IgG concentration 1.0 mg/ml
Buffer Solutions: Phosphate buffered saline pH.4
Target Reference:
1. Durandy, A. et al. (1994) Role of IL-6 in promoting growth of human EBV-induced B-cell tumors in severe combined immunodeficient mice. J. Immunol. 152:5361-5367
2. Lu, Z. et al. (1995) Interleukin-10 is a proliferation factor but not a differentiation factor for human myeloma cells. Blood 85:2521-2527
3. Keller, P. et al. (2005) Interleukin-6 receptor expression in contracting human skeletal muscle: regulating role of IL-6. FASEB J. 19:1181-1183.

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