Catalog No: OPCD08033
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OPCD08033
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Datasheets/ManualsPrintable datasheet for IL6 Recombinant Protein (OPCD08033)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 5% Trehalose.
Host293F cell
ConjugationUnconjugated
ApplicationCtrl (+), SDS-PAGE, WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Phe25-Thr211
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
Source293-F Cells
TagN-terminal His Tag
Gene SymbolIl6
Gene Full Nameinterleukin 6
Alias SymbolsB-cell hybridoma growth factor;Il;Il-6;interleukin HP-1;interleukin-6.
NCBI Gene Id16193
Protein NameInterleukin-6
Description of TargetCytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Uniprot IDP08505
Protein Accession #NP_001300983.1
Nucleotide Accession #NM_001314054.1
Protein Size (# AA)Phe25~Thr211
Molecular Weight27-36kDa
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