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Catalog No: OPCD04417
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OPCD04417
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Datasheets/ManualsPrintable datasheet for IL33 Recombinant Protein (OPCD04417)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser109-Ile266
::Subcellular Location: Nucleus, Secreted, Cytoplasm, Chromosome
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal GST Tag
Gene SymbolIl33
Gene Full Nameinterleukin 33
Alias Symbols9230117N10Rik;Il-;Il1f;Il1f11;Il-33;interleukin-33;NF-H;NF-HEV;nuclear factor from high endothelial venules.
NCBI Gene Id77125
Protein NameInterleukin-33
Description of TargetCytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.
Uniprot IDQ8BVZ5
Protein Accession #NP_001158196.1
Nucleotide Accession #NM_001164724.1
Protein Size (# AA)Ser109~Ile266
Molecular Weight44kDa
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