IL31RA Recombinant Protein (OPCD04413)

Catalog No: OPCD04413

IL31RA Recombinant Protein (OPCD04413) using SDS-PAGE

IL31RA Recombinant Protein (OPCD04413) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val205-Gly456
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: IL31RA
• Gene Full Name: interleukin 31 receptor A
• Alias Symbols: class I cytokine receptor;CRL;CRL3;cytokine receptor-like 3;GLMR;GLM-R;gp130-like monocyte receptor;GPL;hGLM-R;IL-31 receptor subunit alpha;IL-31R subunit alpha;IL-31RA;interleukin-31 receptor subunit alpha;PLCA2;PRO21384;soluble type I cytokine receptor CRL3;zcytoR17.
• NCBI Gene Id: 133396
• Protein Name: Interleukin-31 receptor subunit alpha
• Description of Target: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
• Uniprot ID: Q8NI17
• Protein Accession #: NP_001229565.1
• Nucleotide Accession #: NM_001242636.1
• Protein Size (# AA): Val205~Gly456
• Molecular Weight: 32kDa