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Datasheets/Manuals | Printable datasheet for IL21R Antibody (OAPB00153) (OAPB00153) |
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Predicted Species Reactivity | Bovine|Human|Mouse|Rat |
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Product Format | Liquid. IL-22 Receptor Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Additional Information | HepG2 Cell Lysate (OCPB00171) |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | IL-22 Receptor antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | IL-22 receptor antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor. The immunogen is located within the first 50 amino acids of IL-22 Receptor. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Rat |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-IL21R (OAPB00153) antibody is Catalog # OEPB02260 |
Application Info | IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL and immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 10 ug/mL. |
Reference | Dumoutier L, Louahed J, Renauld JC. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J Immunol. 2000;164(4):1814-9. ;Dumoutier L, Van Roost E, Colau D, Renauld JC. Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc Natl Acad Sci USA . 2000 ;97(18):10144-9.;Xie MH, Aggarwal S, Ho WH, et al. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J Biol Chem. 2000;275(40):31335-9. ;Kotenko SV, Izotova LS, Mirochnitchenko OV, et al. Identification of the functional interleukin-22 (IL-22) receptor complex: J Biol Chem. 2001;276(4):2725-32. |
Gene Symbol | IL22RA1 |
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Gene Full Name | interleukin 22 receptor subunit alpha 1 |
Alias Symbols | CRF2-9;cytokine receptor class-II member 9;cytokine receptor family 2 member 9;IL-22 receptor subunit alpha-1;IL22R;IL22R1;IL-22RA1;IL-22R-alpha-1;interleukin 22 receptor, alpha 1;interleukin-22 receptor subunit alpha-1;zcytoR11. |
NCBI Gene Id | 58985 |
Protein Name | Interleukin-22 receptor subunit alpha-1|interleukin-22 receptor subunit alpha-1 precursor [Homo sapiens] |
Description of Target | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
Uniprot ID | Q8N6P7 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_067081 |
Nucleotide Accession # | NM_021798.3; NM_181078.2; NM_181079.4 |
Molecular Weight | Predicted: 63 kDa Observed: 65 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL21R Antibody (OAPB00153)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Human|Mouse|Rat".
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How long will it take to receive "IL21R Antibody (OAPB00153)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "IL21R Antibody (OAPB00153)" provided in?
This item is provided in "Liquid. IL-22 Receptor Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL21R Antibody (OAPB00153)"?
This target may also be called "CRF2-9;cytokine receptor class-II member 9;cytokine receptor family 2 member 9;IL-22 receptor subunit alpha-1;IL22R;IL22R1;IL-22RA1;IL-22R-alpha-1;interleukin 22 receptor, alpha 1;interleukin-22 receptor subunit alpha-1;zcytoR11." in publications.
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What is the shipping cost for "IL21R Antibody (OAPB00153)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL21R Antibody (OAPB00153)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL21R Antibody (OAPB00153)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 63 kDa Observed: 65 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL21R Antibody (OAPB00153)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL22RA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL22RA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL22RA1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL22RA1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL22RA1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL22RA1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.