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Datasheets/Manuals | Printable datasheet for anti-IL21 antibody - OAAB05527 |
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Predicted Species Reactivity | Human |
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Product Format | Liquid PBS with 0.09% sodium azide |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Host | Rabbit |
Application | WB, IHC-P, FC |
:: | Function: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. Cellular Location: Secreted. Tissue Location: Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This IL21 antibody is generated from rabbits immunized with human IL21. |
Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
Concentration | 0.29 mg/ml |
Sample Type Confirmation | IL21 is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435 |
Application Info | WB: 1:1000 IHC-P: 1:10~50 FC: 1:10~50 |
Other Applications Image 1 Data | IL21 Antibody flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Gene Symbol | IL21 |
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Alias Symbols | Za11, IL-21, CVID11 |
NCBI Gene Id | 59067 |
Protein Name | Interleukin-21 |
Description of Target | L21 may promote the transition between innate and adaptive immunity. It induces the production of IgG(1) and IgG(3) in B-cells (By similarity). It may play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15 and may regulate proliferation of mature B-and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. |
Uniprot ID | Q9HBE4 |
Protein Accession # | NP_001193935.1 |
Molecular Weight | 18 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL21 Antibody (OAAB05527)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL21 Antibody (OAAB05527)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "IL21 Antibody (OAAB05527)" provided in?
This item is provided in "Liquid PBS with 0.09% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL21 Antibody (OAAB05527)"?
This target may also be called "Za11, IL-21, CVID11" in publications.
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What is the shipping cost for "IL21 Antibody (OAAB05527)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL21 Antibody (OAAB05527)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL21 Antibody (OAAB05527)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "18 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL21 Antibody (OAAB05527)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL21"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL21"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL21"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL21"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL21"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL21"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.