IL1A Antibody - N-terminal region (OASG03780)

Catalog No: OASG03780

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC
  Cellular Localization: Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  Sequence & Domain Family: The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human IL-1 Alpha.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: IL-1 Alpha Polyclonal Antibody detects endogenous levels of IL-1 Alpha protein.
• Intended Use: For research use only.
• Application Info: IHC 1:100~300
  ELISA 1:10000

Target Info

• Gene Symbol: IL1A
• Gene Full Name: interleukin 1, alpha
• Alias Symbols: IL1, IL-1A, IL1F1, IL1-ALPHA, IL-1 alpha
• NCBI Gene Id: 3552; 16175; 24493
• Description of Target: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
• Uniprot ID: P01583, P01582, P16598
• Molecular Weight: 31 kDa