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Catalog No: OPCD04316
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OPCD04316
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Datasheets/ManualsPrintable datasheet for IL18R1 Recombinant Protein (OPCD04316)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Tyr375-Glu428
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolIL18R1
Gene Full Nameinterleukin 18 receptor 1
Alias SymbolsCD218 antigen-like family member A;CD218a;CDw218a;cytokine receptor;IL1 receptor-related protein;IL18RA;IL-18Ralpha;IL-18R-alpha;IL18Ralpha2;IL-1Rrp;IL1RRP;interleukin-18 receptor 1;interleukin-18 receptor alpha.
NCBI Gene Id8809
Protein NameInterleukin-18 receptor 1
Description of TargetWithin the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:8626725, PubMed:14528293, PubMed:25261253, PubMed:25500532). Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).
Uniprot IDQ13478
Protein Accession #NP_001269328.1
Nucleotide Accession #NM_001282399.1
Protein Size (# AA)Tyr375~Glu428
Molecular Weight10kDa
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