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Catalog No: OARA02290
Size:100UG
Price: $594.00
SKU
OARA02290
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Il17f Antibody (OARA02290)

Datasheets/ManualsPrintable datasheet for Il17f Antibody (OARA02290)
Product Info
Predicted Species ReactivityMouse
Product FormatLyophilized
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationDot blot|Enzyme-linked immunosorbent assay|Western blot
Reconstitution and StorageStore at 4C prior to restoration. For extended storage, aliquot contents and freeze at -20C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.
ImmunogenThis purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant mouse IL17-F protein.
Concentration1 mg/ml
SpecificityIL-17F antibody has been heated to 56C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant mouse IL17-F in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
Application InfoELISA: 1:10000
WB: 1:1000
This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/ul by the LAL method. By western blot a band approximately 17.9 kDa in size corresponding to mouse IL17-F protein is expected in the appropriate cell lysate or extract. IL-17F forms a disulfide linked homodimer. Specific conditions for reactivity should be optimized by the end user.
ReferenceGomez-Rodriguez,J., Sahu,N., Handon,R., Davidson,T.S., Anderson,S.M., Kirby,M.R., August,A. and Schwartzberg,P.L. (2009) Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity 31 (4), 587-597.Nowak,E.C., Weaver,C.T., Turner,H., Begum-Haque,S., Becher,B., Schreiner,B., Coyle,A.J., Kasper,L.H. and Noelle,R.J. (2009) IL-9 as a mediator of Th17-driven inflammatory disease. J. Exp. Med. 206 (8), 1653-1660.Yu,Y., Iclozan,C., Yamazaki,T., Yang,X., Anasetti,C., Dong,C. and Yu,X.Z. (2009) Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. Blood 114 (5), 1026-1028. (2009)Hymowitz,S.G., Filvaroff,E.H., Yin,J.P., Lee,J., Cai,L., Risser,P., Maruoka,M., Mao,W., Foster,J., Kelley,R.F., Pan,G., Gurney,A.L., de Vos,A.M. and Starovasnik,M.A. (2001) IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J. 20 (19), 5332-5341.
Gene SymbolIl17f
Gene Full Nameinterleukin 17F
Alias SymbolsC87042;IL-17F;interleukin-17F.
NCBI Gene Id257630
Protein NameInterleukin-17F|interleukin-17F precursor [Mus musculus]
Description of TargetLigand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover. Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (By similarity). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (PubMed:15477493).
Uniprot IDQ7TNI7
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_665855.2
  1. What is the species homology for "Il17f Antibody (OARA02290)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".

  2. How long will it take to receive "Il17f Antibody (OARA02290)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "Il17f Antibody (OARA02290)" provided in?

    This item is provided in "Lyophilized".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Il17f Antibody (OARA02290)"?

    This target may also be called "C87042;IL-17F;interleukin-17F." in publications.

  5. What is the shipping cost for "Il17f Antibody (OARA02290)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Il17f Antibody (OARA02290)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Il17f Antibody (OARA02290)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Il17f Antibody (OARA02290)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Il17f"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Il17f"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Il17f"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Il17f"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Il17f"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Il17f"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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