IL-8 Antibody (OADB00383)

Catalog No: OADB00383

Size:500 ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized
• Clonality: Monoclonal
• Clone: B-K8
• Isotype: Mouse IgG1
• Host: Mouse
• Application: BL, FC
• Reconstitution and Storage: Store at +2-8C for 12 months. For longer storage, freeze aliquots
• Purification: Ion exchange chromatography
• Concentration: 1 ug/uL
• Specificity: Recognises both natural and recombinant human IL-8
• Formulation: Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
• Storage Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
• Reference: Schruefer, R. et al, Am J Physiol Heart Circ Physiol.,2005; 288(3): H1186-92.
  Srivani, R. et al.,Current Science,2003;84(3):434-438
  Ulfman, L. H. et al., J Immunol.,2001; 166(1): 588-95.
• Biological Activity: Blocks IL-8 induced chemotaxis of human neutrophils

Target Info

• Gene Symbol: IL-8
• Gene Full Name: C-X-C motif chemokine ligand 8
• Alias Symbols: IL8, NAF, GCP1, LECT, LUCT, NAP1, GCP-1, LYNAP, MDNCF, MONAP, NAP-1, SCYB8
• NCBI Gene Id: 3576
• Protein Name: interleukin-8
• Description of Target: The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
• Protein Accession #: NP_000575.1
• Nucleotide Accession #: NM_000584.3
• Molecular Weight: 11 kDa