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Datasheets/Manuals | Printable datasheet for anti-IL-4 (OADB00369) antibody |
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Predicted Species Reactivity | Human |
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Product Format | Lyophilized |
Clonality | Monoclonal |
Clone | B-S4 |
Isotype | Mouse IgG1 |
Host | Mouse |
Application | BL |
Reconstitution and Storage | Store at +2-8C for 12 months. For longer storage, freeze aliquots |
Purification | Ion exchange chromatography |
Concentration | 1 ug/uL |
Specificity | Recognises both natural and recombinant human IL-4 |
Formulation | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
Storage Buffer | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
Reference | Conticello, C. et al., J Immunol.,2004; 172(9): 5467-77. Koido, S. et al.,J Immunol.,2007; 178(1): 613-22. Koido, S. et al., Clin Cancer Res.,2005; 11(21): 7891-900. Koido, S. et al., J. Immunol.,2007; 179(7): 4874-4883. Stassi, G. et al., Cancer Res.,2003; 63(20): 6784-90. Todaro, M. et al.,Cancer Res.,2006; 66(3): 1491-9. Venet, F. et al.,J Immunol.,2006; 177(9): 6540-7. |
Biological Activity | Blocks IL-4 induced proliferation on TF1 cells |
Gene Symbol | IL-4 |
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Gene Full Name | interleukin 4 |
Alias Symbols | BSF1, IL-4, BCGF1, BSF-1, BCGF-1 |
NCBI Gene Id | 3565 |
Protein Name | interleukin-4 |
Description of Target | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Uniprot ID | P05112 |
Protein Accession # | NP_000580.1 |
Nucleotide Accession # | NM_000589.3 |
Molecular Weight | 17 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL-4 Antibody (OADB00369)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL-4 Antibody (OADB00369)"?
This item is available "Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery".
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What buffer format is "IL-4 Antibody (OADB00369)" provided in?
This item is provided in "Lyophilized".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL-4 Antibody (OADB00369)"?
This target may also be called "BSF1, IL-4, BCGF1, BSF-1, BCGF-1" in publications.
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What is the shipping cost for "IL-4 Antibody (OADB00369)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL-4 Antibody (OADB00369)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL-4 Antibody (OADB00369)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "17 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL-4 Antibody (OADB00369)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL-4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL-4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL-4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL-4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL-4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL-4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.