Catalog No: OOPA00061
Size:2UG
Price: $75.00
SKU
OOPA00061
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Datasheets/Manuals | Printable datasheet for OOPA00061 |
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Predicted Species Reactivity | Human |
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Product Format | Lyophilized from a concentrated (480 ug/ml) sterile solution containing 1x PBS Physical Appearance: Sterile filtered white powder |
Reconstitution and Storage | It is recommended to reconstitute to the lyophilized IL-23 in sterile 18M-omega-cm H2O not less than 100 ug/mL, which can then be further diluted to other aqueous solutions. Lyophilized IL-23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-23 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Concentration | 480 ug/mL (prior to lyophilization) |
Purity | Greater than 95.0% as determined by analysis by SDS-PAGE. |
Biological Activity | The activity, as determined by the dose dependent secretion of h-IFN-g from human PBMC was found to be 2 to 20 ng/mL ED50. |
Source | HEK |
Gene Symbol | IL23 |
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Alias Symbols | Interleukin 23 alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte matur |
Description of Target | IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kB pathways and stimulate the production of interferon-gamma. ). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. |
Protein Size (# AA) | Recombinant |
Molecular Weight | 55 kDa (2 disulfide units--19kDa & 43 kDa) |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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