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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-IL-17A (OADB00329) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Lyophilized |
| Clonality | Monoclonal |
| Clone | B-B51 |
| Isotype | Mouse IgG2b |
| Host | Mouse |
| Application | NT |
| Reconstitution and Storage | Stable at +2-8C for 12 months. For longer storage, freeze aliquots |
| Purification | Ion exchange chromatography |
| Concentration | 1 ug/uL |
| Specificity | Recognizes both recombinant and natural human IL-17A |
| Formulation | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
| Storage Buffer | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
| Biological Activity | Neutralises the bioactivity of IL-17A on keratinocytes cell line HaCaT |
| Gene Symbol | IL-17A |
|---|---|
| Gene Full Name | interleukin 17A |
| Alias Symbols | IL17, CTLA8, IL-17, CTLA-8, IL-17A |
| NCBI Gene Id | 3605 |
| Protein Name | interleukin-17A |
| Description of Target | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
| Uniprot ID | Q16552 |
| Protein Accession # | NP_002181.1 |
| Nucleotide Accession # | NM_002190.2 |
| Molecular Weight | 18 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL-17A Antibody (OADB00329)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL-17A Antibody (OADB00329)"?
This item is available "Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery".
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What buffer format is "IL-17A Antibody (OADB00329)" provided in?
This item is provided in "Lyophilized".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL-17A Antibody (OADB00329)"?
This target may also be called "IL17, CTLA8, IL-17, CTLA-8, IL-17A" in publications.
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What is the shipping cost for "IL-17A Antibody (OADB00329)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL-17A Antibody (OADB00329)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL-17A Antibody (OADB00329)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "18 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL-17A Antibody (OADB00329)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL-17A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL-17A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL-17A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL-17A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL-17A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL-17A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
