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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-IL-12 (OADB00320) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Lyophilized |
| Clonality | Monoclonal |
| Clone | B-P24 |
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Reconstitution and Storage | Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C |
| Purification | Ion exchange chromatography |
| Concentration | 0.1 mg/ml |
| Preservative | Sodium Azide |
| Specificity | Recognises both natural and recombinant IL-12 p40 + p70 |
| Formulation | Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*. |
| Storage Buffer | Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*. |
| Biological Activity | This Antibody can be used as Detection in a human IL-12 sandwich Immunoassay to detect human IL-12 in combination with human IL-12 p40 + p70 Capture Antibody |
| Gene Symbol | IL-12 |
|---|---|
| Gene Full Name | interleukin 12B |
| Alias Symbols | CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B |
| NCBI Gene Id | 3593 |
| Protein Name | interleukin-12 subunit beta |
| Description of Target | This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. |
| Uniprot ID | P29460 |
| Protein Accession # | NP_002178.2 |
| Nucleotide Accession # | NM_002187.2 |
| Molecular Weight | 37 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL-12 p40 + p70 Antibody (OADB00320)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL-12 p40 + p70 Antibody (OADB00320)"?
This item is available "Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery".
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What buffer format is "IL-12 p40 + p70 Antibody (OADB00320)" provided in?
This item is provided in "Lyophilized".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL-12 p40 + p70 Antibody (OADB00320)"?
This target may also be called "CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B" in publications.
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What is the shipping cost for "IL-12 p40 + p70 Antibody (OADB00320)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL-12 p40 + p70 Antibody (OADB00320)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL-12 p40 + p70 Antibody (OADB00320)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "37 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL-12 p40 + p70 Antibody (OADB00320)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL-12"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL-12"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL-12"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL-12"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL-12"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL-12"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
