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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-IL-12 (OADB00315) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Lyophilized |
| Clonality | Monoclonal |
| Clone | B-T21 |
| Isotype | Mouse IgG1 |
| Host | Mouse |
| Application | BL, FC |
| Reconstitution and Storage | Store at +2-8C for 12 months. For longer storage, freeze aliquots |
| Purification | Ion exchange chromatography |
| Concentration | 1 ug/uL |
| Specificity | Recognises both natural and recombinant human IL-12 p35 + p70 |
| Formulation | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
| Storage Buffer | Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free |
| Reference | Kolanowski, S. T. H. M. et al., Innate Immunity,2013: 1753425913498626. Nagai, T. et al., J Immunol.,2003; 171(10): 5233-43. Oppmann, B. et al.,Immunity,2000; 13(5): 715-25. |
| Biological Activity | Blocks IL-12 induced proliferation on PHA and IL-2 activated lymphocytes |
| Gene Symbol | IL-12 |
|---|---|
| Gene Full Name | interleukin 12A |
| Alias Symbols | P35, CLMF, NFSK, NKSF1, IL-12A |
| NCBI Gene Id | 3592 |
| Protein Name | interleukin-12 subunit alpha |
| Description of Target | This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. |
| Uniprot ID | P29459 |
| Protein Accession # | NP_000873.2 |
| Nucleotide Accession # | NM_000882.3 |
| Molecular Weight | 25 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL-12 p35 + p70 Antibody (OADB00315)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL-12 p35 + p70 Antibody (OADB00315)"?
This item is available "Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery".
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What buffer format is "IL-12 p35 + p70 Antibody (OADB00315)" provided in?
This item is provided in "Lyophilized".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL-12 p35 + p70 Antibody (OADB00315)"?
This target may also be called "P35, CLMF, NFSK, NKSF1, IL-12A" in publications.
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What is the shipping cost for "IL-12 p35 + p70 Antibody (OADB00315)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL-12 p35 + p70 Antibody (OADB00315)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL-12 p35 + p70 Antibody (OADB00315)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "25 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL-12 p35 + p70 Antibody (OADB00315)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL-12"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL-12"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL-12"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL-12"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL-12"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL-12"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
