IL 1 Beta Monkey Protein (OPPA02405)

Catalog No: OPPA02405 (Formerly GWB-BSP046)

Size:2UG

Product Info

• Predicted Species Reactivity: Rhesus Monkey
• Product Format: The protein was lyophilized with 1x PBS pH-7.4 Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: E. Coli
• Additional Information: Solubility: It is recommended to reconstitute the lyophilized IL1B in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Biological Activity: The ED50 as determined by the dose-dependant stimulation of D10.G4.1 mouse helper T cells is typically 3-10pg/mL.
  Product Introduction: Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  Product Description: Interleukin-1 beta Monkey Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17.3 kDa. The IL-1b is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized IL1B although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution IL1B should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: APVRSLHCTL RDAQLKSLVM SGPYELKALH LQGQDLEQQV VFSMSFVQGE ESNDKIPVAL GLKAKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTRGG QDITDFTMQF VSS.

Target Info

• Gene Symbol: rmIL1-Beta
• Alias Symbols: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta, IL 1 beta Monkey, Interleukin-1 beta Rhesus Macaque Recombinant
• NCBI Gene Id: 704701
• Protein Name: Interleukin-1 beta
• Description of Target: Recombinant Rhesus Macaque Interleukin-1 beta
• Uniprot ID: P48090
• Protein Accession #: NP_001036221.1
• Protein Size (# AA): Recombinant