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Catalog No: ARP39004_P050
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ARP39004_P050
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Datasheets/ManualsPrintable datasheet for anti-IKZF3 (ARP39004_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human IKZF3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 86%; Dog: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 86%; Rat: 86%
Peptide SequenceSynthetic peptide located within the following region: KSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDDSMKV
Concentration0.5 mg/ml
Blocking PeptideFor anti-IKZF3 (ARP39004_P050) antibody is Catalog # AAP39004 (Previous Catalog # AAPS03701)
ReferenceKoipally,J. (2002) J. Biol. Chem. 277 (31), 27697-27705
Gene SymbolIKZF3
Gene Full NameIKAROS family zinc finger 3 (Aiolos)
Alias SymbolsAIO, AIOLOS, ZNFN1A3
NCBI Gene Id22806
Protein NameZinc finger protein Aiolos
Description of TargetIKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Uniprot IDQ9UKT9-2
Protein Accession #NP_899051
Nucleotide Accession #NM_183228
Protein Size (# AA)453
Molecular Weight52kDa
Protein InteractionsSTAMBPL1; EXOSC5; LGALS14; CABP5; PCID2; RCOR3; TBC1D22B; FANCL; MAGOHB; C1orf109; OAZ3; SPG21; CHCHD2; OSGIN1; POLM; PPP1R16B; ABLIM3; IKZF3; NEK6; FARS2; MRPL28; KAT5; BCAS2; AKAP9; FAM115A; EMC2; POLR1C; STX11; STK16; RAD51D; PSMA1; PRKAB2; PRKAA1; PIN
  1. What is the species homology for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Pig, Rabbit".

  2. How long will it take to receive "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "IKZF3 Antibody - N-terminal region (ARP39004_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    This target may also be called "AIO, AIOLOS, ZNFN1A3" in publications.

  5. What is the shipping cost for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "IKZF3 Antibody - N-terminal region (ARP39004_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "IKZF3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IKZF3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IKZF3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IKZF3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IKZF3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IKZF3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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