- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
IKKB Antibody (Phospho-Ser672) (OAAB16292)
| Datasheets/Manuals | Printable datasheet for OAAB16292 |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid PBS with 0.09% (W/V) sodium azide. |
| Clonality | Polyclonal |
| Isotype | Ig |
| Host | Rabbit |
| Application | DB, ELISA |
| :: | Cellular Location: Cytoplasm. Nucleus. Membrane raft. Note=Colocalized with DPP4 in membrane rafts Tissue Location: Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood. |
| Reconstitution and Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This IKKB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S672 of human IKKB. |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Concentration | 0.5 mg/ml |
| Application Info | DB: 1:500 |
| Description |
| Gene Symbol | IKBKB |
|---|---|
| Alias Symbols | IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta |
| NCBI Gene Id | 3551 |
| Protein Name | Inhibitor of nuclear factor kappa-B kinase subunit beta |
| Description of Target | NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). |
| Uniprot ID | O14920 |
| Protein Accession # | NP_001177649.1 |
| Molecular Weight | 87 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
-
How long will it take to receive "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
-
What buffer format is "IKKB Antibody (Phospho-Ser672) (OAAB16292)" provided in?
This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide. ".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
This target may also be called "IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta" in publications.
-
What is the shipping cost for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "87 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IKKB Antibody (Phospho-Ser672) (OAAB16292)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "IKBKB"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "IKBKB"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "IKBKB"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "IKBKB"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "IKBKB"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "IKBKB"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
