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IKKa/b (Phospho-Ser180/181) Antibody (OAEC01072)

  • Catalog#: OAEC01072
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100ug
$229.00
Discontinued
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Conjugation Options

OAEC01072-FITC Conjugated

OAEC01072-HRP Conjugated

OAEC01072-Biotin Conjugated

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Gene Symbol:
CHUK
Official Gene Full Name:
Inhibitor of nuclear factor kappa-B kinase subunit alpha
NCBI Gene Id:
3551; 1147
Protein Name:
Inhibitor of nuclear factor kappa-B kinase subunit beta
Swissprot Id:
O14920
Protein Accession #:
NP_001177649.1
Molecular Weight:
87 kDa; 85 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation
Application:
WB, IHC, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CHUK.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CHUK.
Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from human IKKa/b around the phosphorylation site of serine 180/181 (C-T-SP-F-V ).
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Reconstitution and Storage:
Store at -20C/1 year
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-IKBKB; CHUK antibody OAEC01072
Specificity:
IKKa/b (Phospho-Ser180/181) antibody detects endogenous levels of IKKa/b only when phosphorylated at serine 180/181.
Formulation:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target Reference:
Mercurio F., et al. (1997) Science 278:860-866. Ling L., Cao Z., et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95:3792-3797. Lubin FD, Sweatt JD (2007) Neuron 55, 942-57. Baeuerle, P.A. and Baltimore, D. (1988) Science 242, 540-6. Beg, A.A. and Baldwin, A.S. (1993) Genes Dev 7, 2064-70. Finco, T.S. et al. (1994) Proc Natl Acad Sci USA 91, 11884-8.

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