IK Recombinant Protein (OPCD04212)

Catalog No: OPCD04212

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Pro192
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: IK
• Gene Full Name: IK cytokine
• Alias Symbols: chondrosarcoma-associated protein 2;CSA2;cytokine IK;IK cytokine, down-regulator of HLA II;IK factor;prer protein;protein Red;Protein RER;RD element;RED;RER.
• NCBI Gene Id: 3550
• Protein Name: Protein Red
• Description of Target: Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression (PubMed:22351768, PubMed:24252166). Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint (PubMed:22351768). Required for normal accumulation of SMU1 (PubMed:24945353).
• Uniprot ID: Q13123
• Protein Accession #: NP_006074.2
• Nucleotide Accession #: NM_006083.3
• Protein Size (# AA): Met1~Pro192
• Molecular Weight: 62kDa