IGFBP2 Antibody (OAGA04332)

Catalog No: OAGA04332

Size:100 ul

Sample (30 ug of whole cell lysate)
A: NT2D1
10% SDS PAGE
diluted at 1:1000

Immunohistochemical analysis of paraffin-embedded human breast cancer, using IGFBP2 antibody at 1:250 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC-P, WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human IGFBP2. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 0.77 mg/ml
• Preservative: 0.01% Thimerosal
• Application Info: Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: IGFBP2
• Gene Full Name: insulin like growth factor binding protein 2
• Alias Symbols: IBP2, IGF-BP53
• NCBI Gene Id: 3485
• Protein Name: insulin-like growth factor-binding protein 2
• Description of Target: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
• Uniprot ID: P18065
• Protein Accession #: NP_000588.2
• Nucleotide Accession #: NM_000597.2