IGF2BP1 Antibody - N-terminal region : HRP (ARP58386_P050-HRP)

Catalog No: ARP58386_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IGF2BP1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: AFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-IGF2BP1 (ARP58386_P050-HRP) antibody is Catalog # AAP58386 (Previous Catalog # AAPS33307)

Target Info

• Reference: Palmer,N.D., (2008) Diabetes 57 (4), 1093-1100
• Gene Symbol: IGF2BP1
• Gene Full Name: Insulin-like growth factor 2 mRNA binding protein 1
• Alias Symbols: IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1
• NCBI Gene Id: 10642
• Protein Name: Insulin-like growth factor 2 mRNA-binding protein 1
• Description of Target: IGF2BP1 is a member of the IGF-II mRNA-binding protein (IMP) family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q9NZI8
• Protein Accession #: NP_006537
• Nucleotide Accession #: NM_006546
• Protein Size (# AA): 577
• Molecular Weight: 63kDa
• Protein Interactions: HAUS2; TUBGCP2; TUBGCP3; TP53; AURKA; CDKN1A; TUBGCP4; CEP250; IVNS1ABP; STAU1; UBC; WWOX; PARK2; FBXO6; BAG3; PAN2; VCAM1; ITGA4; IFIT1; GRB2; FN1; CBX6; CBX8; SYNCRIP; BIRC2; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5; NEDD8; gag; BTRC; ARRB2; Y