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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for IGF1R Antibody (OASA01598) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Phosphate buffered saline |
| Clonality | Monoclonal |
| Clone | 1H7 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | LE: Low Endotoxin |
| Application | Flow cytometry|Functional assay|Immunohistochemistry-Paraffin|Western blot |
| Additional Information | Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0 myeloma cell line. Histology Positive Control Tissue: Pancreas, placenta Endotoxin Level: < 0.01 EU/ug |
| Reconstitution and Storage | -20°C |
| Immunogen | Purified human placental IGF-I receptor. |
| Purification | Protein G Purified |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | 1 mg/ml |
| Specificity | CD221. The ligands for CD221 include IGF-I and IGF-II, which bind to CD221 and activate tyrosine kinase activity, resulting in phosphorylation of several intracellular signaling proteins. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to CD221. |
| Application Info | FC: 1/10. Use 10 uL of the suggested working dilution to label 106 cells in 100 uL. IHC-P: 1/10 - 1/40. This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase. |
| Application Data | Application #1: Staining of human peripheral blood granulocytes with Mouse anti Human CD221  Application #2: Staining of human peripheral blood granulocytes with Mouse anti Human CD221: Alexa Fluor 488  Application #3: Staining of human peripheral blood granulocytes with Mouse anti Human CD221: Low Endotoxin  Application #4: Staining of human peripheral blood granulocytes with Mouse anti Human CD221: RPE  |
| Reference | 1. Li, S.L. et al. (1993) Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor. Biochem. Biophys. Res. Commun. 196:92-98. |
| Gene Symbol | IGF1R |
|---|---|
| Alias Symbols | IGFR, CD221, IGFIR, JTK13 |
| NCBI Gene Id | 3480 |
| Protein Name | Insulin-like growth factor 1 receptor |
| Description of Target | CD221 is a receptor tyrosine kinase. CD221 is composed of two extracellular alpha-subunits and two transmembrane beta-subunits. Clone 1H7 recognizes an epitope in the alpha subunits of CD221, demonstrated by Western blotting. CD221 is expressed in a range of tissues, including kidney, liver, placenta, mammary gland, brain, ovary and skin. |
| Uniprot ID | P08069 |
| Protein Accession # | NP_000866.1 |
| Protein Size (# AA) | 1367 |
| Molecular Weight | ~155 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IGF1R Antibody (OASA01598)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IGF1R Antibody (OASA01598)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "IGF1R Antibody (OASA01598)" provided in?
This item is provided in "Liquid. Phosphate buffered saline".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IGF1R Antibody (OASA01598)"?
This target may also be called "IGFR, CD221, IGFIR, JTK13" in publications.
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What is the shipping cost for "IGF1R Antibody (OASA01598)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IGF1R Antibody (OASA01598)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IGF1R Antibody (OASA01598)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "~155 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IGF1R Antibody (OASA01598)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IGF1R"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IGF1R"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IGF1R"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IGF1R"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IGF1R"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IGF1R"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
