- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for IFNLR1 Antibody (OACA09130) (OACA09130) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Interferon lambda receptor 1 protein (21-228AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Gene Symbol | IFNLR1 |
|---|---|
| Gene Full Name | interferon lambda receptor 1 |
| Alias Symbols | class II cytokine receptor CRF2/12;CRF2/12;CRF2-12;cytokine receptor class-II member 12;cytokine receptor family 2 member 12;IFN-lambda receptor 1;IFN-lambda-R1;IFNLR;IL-28 receptor subunit alpha;IL-28R1;IL28RA;IL-28RA;IL-28R-alpha;interferon lambda receptor 1;interleukin 28 alpha receptor;interleukin 28 receptor A;interleukin 28 receptor, alpha (interferon, lambda receptor);interleukin or cytokine receptor 2;interleukin-28 receptor subunit alpha;LICR2;likely interleukin or cytokine receptor 2. |
| NCBI Gene Id | 163702 |
| Protein Name | Interferon lambda receptor 1 |
| Description of Target | The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. |
| Uniprot ID | Q8IU57 |
| Protein Accession # | NP_734464 |
| Nucleotide Accession # | NM_170743 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "IFNLR1 Antibody (OACA09130)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
-
How long will it take to receive "IFNLR1 Antibody (OACA09130)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
-
What buffer format is "IFNLR1 Antibody (OACA09130)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IFNLR1 Antibody (OACA09130)"?
This target may also be called "class II cytokine receptor CRF2/12;CRF2/12;CRF2-12;cytokine receptor class-II member 12;cytokine receptor family 2 member 12;IFN-lambda receptor 1;IFN-lambda-R1;IFNLR;IL-28 receptor subunit alpha;IL-28R1;IL28RA;IL-28RA;IL-28R-alpha;interferon lambda receptor 1;interleukin 28 alpha receptor;interleukin 28 receptor A;interleukin 28 receptor, alpha (interferon, lambda receptor);interleukin or cytokine receptor 2;interleukin-28 receptor subunit alpha;LICR2;likely interleukin or cytokine receptor 2." in publications.
-
What is the shipping cost for "IFNLR1 Antibody (OACA09130)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "IFNLR1 Antibody (OACA09130)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "IFNLR1 Antibody (OACA09130)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IFNLR1 Antibody (OACA09130)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "IFNLR1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "IFNLR1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "IFNLR1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "IFNLR1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "IFNLR1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "IFNLR1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
