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Datasheets/Manuals | Printable datasheet for IFN-GAMMA Antibody (OAAD00252) - OAAD00252 |
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Predicted Species Reactivity | Human |
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Clonality | Monoclonal |
Clone | 1B1A4, E8H1 |
Isotype | IgG1 |
Host | Mouse |
Application | WB |
Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
Immunogen | Recombinant human IFN-gamma (BioSource company, Cat.No. PHC4033) |
Formulation | Purified antibody in PBS containing 0.03% sodium azide. |
Application Info | Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test. |
Reference | 1. Dean GA. LaVoy A. Burkhard MJ. Vet Immunol Immunopathol. 2004, Jul, 100(1-2):49-59. 2. Arens R. Schepers K. Nolte MA. et al. J Exp Med. 2004, Jun 7, 199(11):1595-605. 3. Podhorecka M. Dmoszynska A. Rolinski J. Eur J Haematol. 2004, Jul, 73(1):29-35. |
Gene Symbol | IFN-Gamma |
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Alias Symbols | IFG, IFI, IMD69 |
NCBI Gene Id | 3458 |
Description of Target | IFN-gamma (interferon, gamma) is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. The active form of IFN-G is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-G is stabilized by non-covalent interactions through the interface of the helices. IFN-G translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers. |
Uniprot ID | P01579 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IFN-GAMMA Antibody (OAAD00252)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IFN-GAMMA Antibody (OAAD00252)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "IFN-GAMMA Antibody (OAAD00252)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IFN-GAMMA Antibody (OAAD00252)"?
This target may also be called "IFG, IFI, IMD69" in publications.
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What is the shipping cost for "IFN-GAMMA Antibody (OAAD00252)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IFN-GAMMA Antibody (OAAD00252)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IFN-GAMMA Antibody (OAAD00252)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IFN-GAMMA Antibody (OAAD00252)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IFN-GAMMA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IFN-GAMMA"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IFN-GAMMA"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IFN-GAMMA"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IFN-GAMMA"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IFN-GAMMA"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.