ID2 Antibody (OAAJ06652)

Catalog No: OAAJ06652

Size:100 uL

Western blot analysis of 293T cell lysate using ID2 antibody.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
• Immunogen: Recombinant proteinof human ID2
• Purification: Immunogen affinity chromatography
• Concentration: 1 mg/mL

Target Info

• Gene Symbol: ID2
• Alias Symbols: GIG8, ID2A, ID2H, bHLHb26
• NCBI Gene Id: 3398
• Protein Name: DNA-binding protein inhibitor ID-2
• Description of Target: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
• Uniprot ID: Q02363
• Protein Accession #: NP_002157
• Nucleotide Accession #: NM_002166
• Molecular Weight: 18 kDa