ICK Recombinant Protein (OPCD04083)

Catalog No: OPCD04083

ICK Recombinant Protein (OPCD04083) using SDS-PAGE

ICK Recombinant Protein (OPCD04083) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Phe284
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CILK1
• Gene Full Name: ciliogenesis associated kinase 1
• Alias Symbols: ECO;EJM10;hICK;iciliogenesis associated kinase 1;ICK;intestinal cell (MAK-like) kinase;intestinal cell kinase;laryngeal cancer kinase 2;LCK2;MAK-related kinase;MRK;serine/threonine protein kinase;serine/threonine-protein kinase ICK.
• NCBI Gene Id: 22858
• Protein Name: Serine/threonine-protein kinase ICK
• Description of Target: Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).
• Uniprot ID: Q9UPZ9
• Protein Accession #: NP_055735.1
• Nucleotide Accession #: NM_014920.3
• Protein Size (# AA): Met1~Phe284
• Molecular Weight: 37kDa