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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for ICAM1 Antibody (OAEE00274) (OAEE00274) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | MEM-112 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | Flow cytometry|Immunoprecipitation |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Raji Burkitt's lymphoma cell line Raji |
| Purification | Purified |
| Concentration | 1 mg/ml |
| Specificity | The antibody MEM-112 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. HLDA VI; WS Code AS A050 |
| Formulation | Purified |
| Purity | > 95% (by SDS-PAGE) |
| Storage Buffer | Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0 |
| Reference | Leeuwenberg JF, Smeets EF, Neefjes JJ, Shaffer MA, Cinek T, Jeunhomme TM, Ahern TJ, Buurman WA.: E-selectin and intercellular adhesion molecule-1 are released by activatedhuman endothelial cells in vitro. Immunology. 1992 Dec;77(4):543-9. Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997). |
| Gene Symbol | ICAM1 |
|---|---|
| Gene Full Name | intercellular adhesion molecule 1 |
| Alias Symbols | BB2;CD54;cell surface glycoprotein P3.58;epididymis secretory sperm binding protein;ICAM-1;intercellular adhesion molecule 1;intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;major group rhinovirus receptor;P3.58. |
| NCBI Gene Id | 3383 |
| Protein Name | Intercellular adhesion molecule 1 |
| Description of Target | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
| Uniprot ID | P05362 |
| Protein Accession # | NP_000192.2 |
| Nucleotide Accession # | NM_000201.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ICAM1 Antibody (OAEE00274)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ICAM1 Antibody (OAEE00274)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "ICAM1 Antibody (OAEE00274)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ICAM1 Antibody (OAEE00274)"?
This target may also be called "BB2;CD54;cell surface glycoprotein P3.58;epididymis secretory sperm binding protein;ICAM-1;intercellular adhesion molecule 1;intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;major group rhinovirus receptor;P3.58." in publications.
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What is the shipping cost for "ICAM1 Antibody (OAEE00274)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ICAM1 Antibody (OAEE00274)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ICAM1 Antibody (OAEE00274)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ICAM1 Antibody (OAEE00274)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ICAM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ICAM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ICAM1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ICAM1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ICAM1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ICAM1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
