Human CTGF Protein (OPSA11023)

Catalog No: OPSA11023 (Formerly GWB-2A2250)

Size:20UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Lyophilized. 10mM Sodium Acetate
• Application: Enzyme-linked immunosorbent assay|Functional assay|Western blot
• Additional Information: Activity: Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED₅₀ for this effect is 1.0-2.0 ug/ml.
  Approx Protein Conc: Total protein concentration 0.1mg/ml after reconstitution
  Buffer solution: 10mM Sodium Acetate
  Endotoxin Level: < 1EU/ug
  Label Protein Molar Ratio: Purified recombinant CTGF expressed in E.coli
  Preservative: None present
• Reconstitution and Storage: -20°C
• Predicted Homology Based on Immunogen Sequence: Human
• Purification: Purified recombinant CTGF expressed in E.coli
• Concentration: 0.1 mg/ml
• Purity: >95% by SDS PAGE/HPLC analysis
• Specificity: CTGF (connective tissue growth factor) is a heparin-binding pleiotropic growth factor and member of the CCN family of secreted cysteine rich regulatory proteins, which interacts with other growth factors including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs).
  CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF is involved in chondrogenesis and potentially skeletogenesis, induces extracellular matrix formation and has also been implicated in wound healing.
  
• Application Info: ELISA:    0.2 - 0.4ng/well
  Western Blotting:    1.5 - 3.0ng/lane
  Functional Assays:    1.0 - 2.0ug/ml
  

Target Info

• Gene Symbol: CTGF
• Alias Symbols: CTGF, NOV2, HCS24, IGFBP8
• NCBI Gene Id: 1490
• Protein Name: Connective tissue growth factor
• Description of Target: RECOMBINANT HUMAN CTGF
  
• Uniprot ID: P29279
• Protein Accession #: NP_001892.1
• Protein Size (# AA): Recombinant
• Molecular Weight: 11.2kD (98 amino acid residues)