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Human CD253 Protein (OPSA11007)

Catalog#: OPSA11007
This product is Genway GWB-F7C0B1
More Information
Predicted Species Reactivity Human
Product Format Purified recombinant protein - lyophilised
Additional Information Approx Protein Conc: 1.0 mg/ml
Buffer solution: Phosphate buffered saline
:: Endotoxin Level: < 0.1ng/ug
:: Label Protein Molar Ratio: Recombinant protein expressed in E.coli
Preservative: None present
Reconstitution and Storage Reconstitution: Reconstitute with 50ul distilled water
Storage: Prior to reconstitution store at +4oC. Following reconstitution store at -20oC.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Predicted Homology Based on Immunogen Sequence Human
Purity >98% by SDS PAGE and HPLC analysis
Specificity TRAIL (TNF-related Apoptosis Inducing Ligand) also known as CD253, is a cytotoxic protein which activates apoptosis in tumour cells but not in normal cells.
TRAIL binds to two so-called 'death receptors', designated DR4 and DR5.
Application Info Functional Assays:    0.2ng/ml - 20ng/ml
following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information.
 YesNoNot DeterminedSuggested Dilution
Functional Assays    0.2ng/ml - 20ng/ml
Where this protein has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the protein for use in their own system using appropriate positive/negative controls.
Datasheets/Manuals Printable datasheet for OPSA11007
Gene Symbol TNFSF10
Alias Symbols TL2, APO2L, CD253, TRAIL, Apo-2L, TNFSF10
NCBI Gene Id 8743
Protein Name Tumor necrosis factor ligand superfamily member 10
Description of Target RECOMBINANT HUMAN CD253
Swissprot Id P50591
Protein Accession # NP_003801.1
Protein Size (# AA) 281
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express TNFSF10.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express TNFSF10.
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