- Gene Symbol:
- Alias Symbols:
- TL2, APO2L, CD253, TRAIL, Apo-2L, TNFSF10
- NCBI Gene Id:
- Swissprot Id:
- Protein Accession #:
- Protein Name:
- Tumor necrosis factor ligand superfamily member 10
- Description of Target:
- RECOMBINANT HUMAN CD253
- Protein Size (# AA):
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express TNFSF10.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express TNFSF10.
- Product Format:
- Purified recombinant protein - lyophilised
- Predicted Homology Based on Immunogen Sequence:
- Predicted Species Reactivity:
- >98% by SDS PAGE and HPLC analysis
- TRAIL (TNF-related Apoptosis Inducing Ligand) also known as CD253, is a cytotoxic protein which activates apoptosis in tumour cells but not in normal cells.
TRAIL binds to two so-called 'death receptors', designated DR4 and DR5.
- Application Info:
- Functional Assays: 0.2ng/ml - 20ng/ml
following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information.
- Additional Information:
- Approx Protein Conc: 1.0 mg/ml
Buffer solution: Phosphate buffered saline
- Endotoxin Level: < 0.1ng/ug
- Label Protein Molar Ratio: Recombinant protein expressed in E.coli
Preservative: None present
- Reconstitution and Storage:
- Reconstitution: Reconstitute with 50ul distilled water
Storage: Prior to reconstitution store at +4oC. Following reconstitution store at -20oC.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- Printable datasheet for OPSA11007
|Yes||No||Not Determined||Suggested Dilution|
|Functional Assays||0.2ng/ml - 20ng/ml|
Where this protein has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the protein for use in their own system using appropriate positive/negative controls.
- Tips Information: