Human CD253 Protein (OPSA11007)
This product is Genway GWB-F7C0B1
|Predicted Species Reactivity||Human|
|Product Format||Purified recombinant protein - lyophilised|
|Additional Information||Approx Protein Conc: 1.0 mg/ml
Buffer solution: Phosphate buffered saline
|::||Endotoxin Level: < 0.1ng/ug|
|::||Label Protein Molar Ratio: Recombinant protein expressed in E.coli
Preservative: None present
|Reconstitution and Storage||Reconstitution: Reconstitute with 50ul distilled water
Storage: Prior to reconstitution store at +4oC. Following reconstitution store at -20oC.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
|Predicted Homology Based on Immunogen Sequence||Human|
|Purity||>98% by SDS PAGE and HPLC analysis|
|Specificity||TRAIL (TNF-related Apoptosis Inducing Ligand) also known as CD253, is a cytotoxic protein which activates apoptosis in tumour cells but not in normal cells.
TRAIL binds to two so-called 'death receptors', designated DR4 and DR5.
|Application Info||Functional Assays: 0.2ng/ml - 20ng/ml
following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information.
Where this protein has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the protein for use in their own system using appropriate positive/negative controls.
|Datasheets/Manuals||Printable datasheet for OPSA11007|
|Alias Symbols||TL2, APO2L, CD253, TRAIL, Apo-2L, TNFSF10|
|NCBI Gene Id||8743|
|Protein Name||Tumor necrosis factor ligand superfamily member 10|
|Description of Target||RECOMBINANT HUMAN CD253
|Protein Accession #||NP_003801.1|
|Protein Size (# AA)||281|
|Tissue Tool||Find tissues and cell lines supported by DNA array analysis to express TNFSF10.|
|RNA Seq||Find tissues and cell lines supported by RNA-seq analysis to express TNFSF10.|
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
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