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Human CD253 Protein (OPSA11007)

50 ug
In Stock
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Gene Symbol:
Alias Symbols:
TL2, APO2L, CD253, TRAIL, Apo-2L, TNFSF10
NCBI Gene Id:
Swissprot Id:
Protein Accession #:
Protein Name:
Tumor necrosis factor ligand superfamily member 10
Description of Target:
Protein Size (# AA):
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TNFSF10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TNFSF10.
Product Format:
Purified recombinant protein - lyophilised
Predicted Homology Based on Immunogen Sequence:
Predicted Species Reactivity:
>98% by SDS PAGE and HPLC analysis
TRAIL (TNF-related Apoptosis Inducing Ligand) also known as CD253, is a cytotoxic protein which activates apoptosis in tumour cells but not in normal cells.
TRAIL binds to two so-called 'death receptors', designated DR4 and DR5.
Application Info:
Functional Assays:    0.2ng/ml - 20ng/ml
following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information.
 YesNoNot DeterminedSuggested Dilution
Functional Assays    0.2ng/ml - 20ng/ml
Where this protein has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the protein for use in their own system using appropriate positive/negative controls.
Additional Information:
Approx Protein Conc: 1.0 mg/ml
Buffer solution: Phosphate buffered saline
Endotoxin Level: < 0.1ng/ug
Label Protein Molar Ratio: Recombinant protein expressed in E.coli
Preservative: None present
Reconstitution and Storage:
Reconstitution: Reconstitute with 50ul distilled water
Storage: Prior to reconstitution store at +4oC. Following reconstitution store at -20oC.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Printable datasheet for OPSA11007

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