HTRA1 Recombinant Protein (OPCD04050)

Catalog No: OPCD04050

HTRA1 Recombinant Protein (OPCD04050) using SDS-PAGE

HTRA1 Recombinant Protein (OPCD04050) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Escherichia coli
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala10-Gly146
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: degP
• Gene Full Name: periplasmic serine endoprotease DegP
• Alias Symbols: b0161;ECK0160;Heat shock protein DegP;htrA;periplasmic serine endoprotease DegP;Protease Do;ptd.
• NCBI Gene Id: 947139
• Protein Name: Periplasmic serine endoprotease DegP
• Description of Target: DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures (PubMed:10319814). Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm following heat shock or other stress conditions (PubMed:16303867). DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids (PubMed:8830688). Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins (PubMed:8830688). Its proteolytic activity is essential for the survival of cells at elevated temperatures (PubMed:7557477). It can degrade IciA, Ada, casein, globin and PapA. DegP shares specificity with DegQ (PubMed:8830688). DegP is also involved in the biogenesis of partially folded outer-membrane proteins (OMP).
• Uniprot ID: P0C0V0
• Protein Size (# AA): Ala10~Gly146
• Molecular Weight: 16kDa