Catalog No: OAAJ04380
Size:100 uL
Price: $319.00
SKU
OAAJ04380
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-HTR2B (OAAJ04380) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationWB, IHC, IF, ICC
Reconstitution and StorageStore at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
ImmunogenA synthesized peptide
PurificationImmunogen affinity chromatography
Concentration1 mg/mL
Gene SymbolHTR2B
Alias Symbols5-HT2B, 5-HT-2B, 5-HT(2B)
NCBI Gene Id3357
Protein Name5-hydroxytryptamine receptor 2B
Description of TargetG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.
Uniprot IDP41595
Protein Accession #NP_000858
Nucleotide Accession #NM_000867
Molecular Weight54 kDa
  1. What is the species homology for "HTR2B Antibody (OAAJ04380)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "HTR2B Antibody (OAAJ04380)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "HTR2B Antibody (OAAJ04380)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HTR2B Antibody (OAAJ04380)"?

    This target may also be called "5-HT2B, 5-HT-2B, 5-HT(2B)" in publications.

  5. What is the shipping cost for "HTR2B Antibody (OAAJ04380)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HTR2B Antibody (OAAJ04380)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HTR2B Antibody (OAAJ04380)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "54 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HTR2B Antibody (OAAJ04380)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HTR2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HTR2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HTR2B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HTR2B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HTR2B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HTR2B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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