Catalog No: OAAB18138
Size:400ul
Price: $450.00
SKU
OAAB18138
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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Datasheets/ManualsPrintable datasheet for OAAB18138
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationWB, FC
::Cellular Location: Cell membrane; Multi-pass membrane protein.
Tissue Location Detected in lymph nodes, thymus and spleen. Detected in activated T-cells, but not in resting T-cells.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Intended UseFor research use only and not for use in diagnostic or therapeutic procedures.
Application InfoFC: 1:25
WB: 1:1000
ReferenceKobilka B.K., et al.Nature 329:75-79(1987).
Saltzman A.G., et al.Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases.
Levy F.O., et al.Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases.
Kitano T., et al.Mol. Biol. Evol. 21:936-944(2004).
Puhl H.L. III, et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Gene SymbolHTR1A
Alias SymbolsG-21, 5HT1a, PFMCD, 5-HT1A, 5-HT-1A, ADRBRL1, ADRB2RL1
NCBI Gene Id3350
Description of TargetG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Uniprot IDP08908
Molecular Weight46 kDa
  1. What is the species homology for "HTR1A Antibody - middle region (OAAB18138)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "HTR1A Antibody - middle region (OAAB18138)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "HTR1A Antibody - middle region (OAAB18138)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HTR1A Antibody - middle region (OAAB18138)"?

    This target may also be called "G-21, 5HT1a, PFMCD, 5-HT1A, 5-HT-1A, ADRBRL1, ADRB2RL1" in publications.

  5. What is the shipping cost for "HTR1A Antibody - middle region (OAAB18138)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HTR1A Antibody - middle region (OAAB18138)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HTR1A Antibody - middle region (OAAB18138)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "46 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HTR1A Antibody - middle region (OAAB18138)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HTR1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HTR1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HTR1A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HTR1A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HTR1A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HTR1A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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