HSPH1 Recombinant Protein (OPCD04047)

Catalog No: OPCD04047

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Lys388-Glu505
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: HSPH1
• Gene Full Name: heat shock protein family H (Hsp110) member 1
• Alias Symbols: antigen NY-CO-25;heat shock 105kDa/110kDa protein 1;Heat shock 110 kDa protein;heat shock protein 105 kDa;HSP105;HSP105A;HSP105B;NY-CO-25.
• NCBI Gene Id: 10808
• Protein Name: Heat shock protein 105 kDa
• Description of Target: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
• Uniprot ID: Q92598
• Protein Accession #: NP_001273432.1
• Nucleotide Accession #: NM_001286503.1
• Protein Size (# AA): Lys388~Glu505
• Molecular Weight: 14.55kDa