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HSPH1 Antibody - middle region (ARP52217_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP52217_P050-FITC Conjugated

ARP52217_P050-HRP Conjugated

ARP52217_P050-Biotin Conjugated

Gene Symbol:
HSPH1
Official Gene Full Name:
Heat shock 105kDa/110kDa protein 1
NCBI Gene Id:
10808
Protein Name:
Heat shock protein 105 kDa
Swissprot Id:
Q92598
Protein Accession #:
NP_006635
Nucleotide Accession #:
NM_006644
Alias Symbols:
DKFZp686M05240, HSP105, HSP105A, HSP105B, KIAA0201, NY-CO-25
Replacement Item:
This antibody may replace item sc-135942 from Santa Cruz Biotechnology.
Description of Target:
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities.
Protein Size (# AA):
858
Molecular Weight:
97kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HSPH1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HSPH1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human HSPH1
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-HSPH1 (ARP52217_P050)
Peptide Sequence:
Synthetic peptide located within the following region: EENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQ
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
HUWE1; UBC; SUMO2; SUMO3; HSPA8; MDM2; ILK; SET; PPM1G; PLOD2; HSPA4; DPYSL2; CTNNA1; PARVA; PUS7; SAMHD1; XPO7; FAF1; CARM1; SEC23A; PRMT3; FARSB; RANBP3; HIRIP3; HIST1H4A; USP11; SF1; UGP2; HECW2; FBXO6; TARDBP; CFTR; METTL21A; env; NOS2; HSP90AB1; HSP9
Blocking Peptide:
For anti-HSPH1 (ARP52217_P050) antibody is Catalog # AAP52217 (Previous Catalog # AAPY03639)
Datasheets/Manuals:
Printable datasheet for anti-HSPH1 (ARP52217_P050) antibody
Sample Type Confirmation:

HSPH1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, MCF7

Target Reference:
Meares,G.P., (2008) Cell. Signal. 20 (2), 347-358
Publications:

Du, ZN; Rong, CT; Hui, S; Peng, Z; Jin, SH; Li, SJ; Wang, HY; Li, JY; Expression and function of HSP110 family in mouse testis after vasectomy. , (2016). WB, IHC, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 26952955

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