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HSPB1 Antibody - C-terminal region (ARP30177_T100)

100 ul
$229.00
In Stock
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Conjugation Options

ARP30177_T100-FITC Conjugated

ARP30177_T100-HRP Conjugated

ARP30177_T100-Biotin Conjugated

Gene Symbol:
HSPB1
Official Gene Full Name:
Heat shock 27kDa protein 1
NCBI Gene Id:
3315
Protein Name:
Heat shock protein beta-1
Swissprot Id:
P04792
Protein Accession #:
NP_001531
Nucleotide Accession #:
NM_001540
Alias Symbols:
CMT2F, DKFZp586P1322, HS.76067, HSP27, HSP28, Hsp25, HMN2B, SRP27
Replacement Item:
This antibody may replace item sc-1048 from Santa Cruz Biotechnology.
Description of Target:
HSPB1, like the other heat shock proteins, is part of a complex system of molecular chaperones in epidermal keratinocytes.
Protein Size (# AA):
205
Molecular Weight:
23kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HSPB1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HSPB1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human HSPB1
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human: 100%
Complete computational species homology data:
Anti-HSPB1 (ARP30177_T100)
Peptide Sequence:
Synthetic peptide located within the following region: SLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
PCSK9; HUWE1; UBC; GATA1; MAPKAPK2; AKT1; CRYAB; MAP3K7; SUMO2; HAUS1; CEP57; AARSD1; BAG3; IRS4; HSF1; LCE3A; TGFB1I1; SUMO1; NEDD8; MDM2; ASB6; ASB10; ASB17; WWOX; ASB4; ZBTB1; RPA3; RPA2; RPA1; EZH2; ESR1; SOX2; NPM1; PLG; CS; MAPKAPK3; INS; HSPB1; SGA
Blocking Peptide:
For anti-HSPB1 (ARP30177_T100) antibody is Catalog # AAP30177 (Previous Catalog # AAPS08907)
Datasheets/Manuals:
Printable datasheet for anti-HSPB1 (ARP30177_T100) antibody
Target Reference:
Boncinelli,E., (2006) J. Biol. Chem. 281 (12), 8169-8174
Publications:

Narjoz, C. et al. Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells. Chem. Res. Toxicol. 22, 779-87 (2009). IHC, WB, Human 19445531

Sookoian, S; Castaño, GO; Scian, R; San Martino, J; Pirola, CJ; Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH). 6, 22528 (2016). IHC, WB, Human 26935030

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