HSPA1A Antibody (Acetyl-Lys246) (OASG00150)

Catalog No: OASG00150

Size:100 uL

Western Blot using Rat Kidney

Western Blot using Rat Kidney

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human HSP70 around the acetylation site of K246.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Acetyl-Lys246
• Specificity: Acetyl-HSP70 (K246) Polyclonal Antibody detects endogenous levels of HSP70 protein only when non-acetylation at K246.
• Application Info: WB 1:500-1:2000; ELISA 1:10000;

Target Info

• Gene Symbol: HSPA1A, HSPA1B
• Gene Full Name: heat shock 70kDa protein 1A
• Alias Symbols: HSP72, HSPA1, HSP70I, HSP70-1, HSP70-2, HSP70.1, HSP70.2, HSP70-1A, HEL-S-103
• NCBI Gene Id: 3303; 3304;
• Description of Target: This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
• Uniprot ID: P08107