HSF1 Antibody - C-terminal region : Biotin (P100769_P050-Biotin)

Catalog No: P100769_P050-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HSF1
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 85%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 85%
• Peptide Sequence: Synthetic peptide located within the following region: SVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-HSF1 (P100769_P050-Biotin) antibody is Catalog # AAP31096 (Previous Catalog # AAPP01835)
• Reference: Wang,J., et al., (2006) J. Biol. Chem. 281 (5), 2451-2459

Target Info

• Gene Symbol: HSF1
• Gene Full Name: Heat shock transcription factor 1
• Alias Symbols: HSTF1
• NCBI Gene Id: 3297
• Protein Name: Heat shock factor protein 1
• Description of Target: HSF1 is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of HSF1.HSF1 is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of HSF1.
• Uniprot ID: Q00613
• Protein Accession #: NP_005517
• Nucleotide Accession #: NM_005526
• Protein Size (# AA): 529
• Molecular Weight: 57kDa
• Protein Interactions: HSP90AA1; SUMO2; SUMO3; NME2; KPNA4; KPNA3; HSPB1; HSF4; HSF2; HSPBP1; HSPA4L; BAG3; UBC; CBS; CALU; AARS; AAMP; TPRKB; PLIN3; ARPC1B; KIAA0101; MTMR2; ZPR1; UBE3A; SURF2; SRP9; HSPA8; DR1; DHPS; DTD1; BTF3L4; LRSAM1; C14orf142; GOPC; ANKMY2; CTPS2; RPRD1