Catalog No: ARP41529_T100-Biotin
Size:100ul
Price: $384.00
SKU
ARP41529_T100-Biotin
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HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)

Datasheets/ManualsPrintable datasheet for anti-HSD17B6 (ARP41529_T100-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationIHC, WB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B6
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLD
Concentration0.5 mg/ml
Blocking PeptideFor anti-HSD17B6 (ARP41529_T100-Biotin) antibody is Catalog # AAP41529 (Previous Catalog # AAPP24215)
Sample Type Confirmation

HSD17B6 is strongly supported by BioGPS gene expression data to be expressed in A172

ReferenceHuang,X.F. (2001) Biochim. Biophys. Acta 1520 (2), 124-130
Publications

Mohler, J. L. et al. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res. 71, 1486-96 (2011). WB, IHC, Human, Mouse, Dog, Rat, Pig, Guinea pig, Bovine, Horse, Rabbit 21303972

Muthusamy, S. et al. Estrogen receptor β and 17β-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer. Proc. Natl. Acad. Sci. U. S. A. 108, 20090-4 (2011). WB, IHC, Human, Mouse, Dog, Rat, Pig, Guinea pig, Bovine, Horse, Rabbit 22114194

Gene SymbolHSD17B6
Gene Full NameHydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
Alias SymbolsHSE, RODH, SDR9C6
NCBI Gene Id8630
Protein Name17-beta-hydroxysteroid dehydrogenase type 6
Description of TargetHSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
Uniprot IDO14756
Protein Accession #NP_003716
Nucleotide Accession #NM_003725
Protein Size (# AA)317
Molecular Weight35kDa
  1. What is the species homology for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    This target may also be called "HSE, RODH, SDR9C6" in publications.

  5. What is the shipping cost for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "35kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HSD17B6 Antibody - N-terminal region : Biotin (ARP41529_T100-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "HSD17B6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HSD17B6"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HSD17B6"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HSD17B6"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HSD17B6"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HSD17B6"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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