Catalog No: OPCD03991
Price: $0.00
SKU
OPCD03991
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Datasheets/Manuals | Printable datasheet for HSD17B12 Recombinant Protein (OPCD03991) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Met1-Asn312 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 97% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | HSD17B12 |
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Gene Full Name | hydroxysteroid 17-beta dehydrogenase 12 |
Alias Symbols | 17-beta-HSD 12;17beta-HSD type 12;17-beta-hydroxysteroid dehydrogenase 12;3-ketoacyl-CoA reductase;estradiol 17-beta-dehydrogenase 12;KAR;SDR12C1;short chain dehydrogenase/reductase family 12C member 1;steroid dehydrogenase homolog;very-long-chain 3-oxoacyl-CoA reductase. |
NCBI Gene Id | 51144 |
Protein Name | Very-long-chain 3-oxoacyl-CoA reductase |
Description of Target | Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation. |
Uniprot ID | Q53GQ0 |
Protein Accession # | NP_057226.1 |
Nucleotide Accession # | NM_016142.2 |
Protein Size (# AA) | Met1~Asn312 |
Molecular Weight | 38kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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