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Catalog No: OPCD03986
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OPCD03986
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Datasheets/ManualsPrintable datasheet for HSD11B2 Recombinant Protein (OPCD03986)
Product Info
Predicted Species ReactivityRat|Rattus norvegicus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Leu58-Pro393
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolHsd11b2
Gene Full Namehydroxysteroid 11-beta dehydrogenase 2
Alias Symbols11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;11-DH2;corticosteroid 11-beta-dehydrogenase isozyme 2;Hydroxysteroid dehydrogenase, 11 beta type 2;NAD-dependent 11-beta-hydroxysteroid dehydrogenase.
NCBI Gene Id25117
Protein NameCorticosteroid 11-beta-dehydrogenase isozyme 2
Description of TargetCatalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Uniprot IDP50233
Protein Accession #NP_058777.1
Nucleotide Accession #NM_017081.2
Protein Size (# AA)Leu58~Pro393
Molecular Weight41kDa
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