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HRK antibody - N-terminal region (ARP46364_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP46364_P050-FITC Conjugated

ARP46364_P050-HRP Conjugated

ARP46364_P050-Biotin Conjugated

Gene Symbol:
HRK
NCBI Gene Id:
8739
Official Gene Full Name:
Harakiri, BCL2 interacting protein (contains only BH3 domain)
Protein Name:
Activator of apoptosis harakiri
Swissprot Id:
O00198
Protein Accession #:
NP_003797
Nucleotide Accession #:
NM_003806
Alias Symbols:
DP5, HARAKIRI
Replacement Item:
This antibody may replace item sc-26825 from Santa Cruz Biotechnology.
Description of Target:
Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
Protein Size (# AA):
91
Molecular Weight:
10kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HRK.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HRK.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%
Complete computational species homology data:
Anti-HRK (ARP46364_P050)
Peptide Sequence:
Synthetic peptide located within the following region: MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMW
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
BCL2L1; ELAVL1; BAD; BCL2L2; C1QBP; BCL2A1; BCL2; MCL1; BNC1;
Blocking Peptide:
For anti-HRK (ARP46364_P050) antibody is Catalog # AAP46364 (Previous Catalog # AAPP27150)
Datasheets/Manuals:
Printable datasheet for anti-HRK (ARP46364_P050) antibody
Publications:

Lucas, CM; Milani, M; Butterworth, M; Carmell, N; Scott, LJ; Clark, RE; Cohen, GM; Varadarajan, S; High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia. 30, 1273-81 (2016). WB, Cow, Dog, Human, Mouse, Rabbit, Rat 26987906

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