Size:100 ul
Special Price $229.00 Regular Price $289.00
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SKU
ARP46364_P050
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Conjugation Options

ARP46364_P050-FITC Conjugated

ARP46364_P050-HRP Conjugated

ARP46364_P050-Biotin Conjugated

HRK Antibody - N-terminal region (ARP46364_P050)

Catalog#: ARP46364_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Human, Mouse, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-26825 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%
Complete computational species homology data Anti-HRK (ARP46364_P050)
Peptide Sequence Synthetic peptide located within the following region: MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMW
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-HRK (ARP46364_P050) antibody is Catalog # AAP46364 (Previous Catalog # AAPP27150)
Datasheets/Manuals Printable datasheet for anti-HRK (ARP46364_P050) antibody
Publications

Lucas, CM; Milani, M; Butterworth, M; Carmell, N; Scott, LJ; Clark, RE; Cohen, GM; Varadarajan, S; High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia. 30, 1273-81 (2016). WB, Cow, Dog, Human, Mouse, Rabbit, Rat 26987906

Gene Symbol HRK
Official Gene Full Name Harakiri, BCL2 interacting protein (contains only BH3 domain)
Alias Symbols DP5, HARAKIRI
NCBI Gene Id 8739
Protein Name Activator of apoptosis harakiri
Description of Target Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
Swissprot Id O00198
Protein Accession # NP_003797
Nucleotide Accession # NM_003806
Protein Size (# AA) 91
Molecular Weight 10kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express HRK.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express HRK.
Protein Interactions BCL2L1; ELAVL1; BAD; BCL2L2; C1QBP; BCL2A1; BCL2; MCL1; BNC1;
  1. What is the species homology for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Human, Mouse, Rabbit, Rat".

  2. How long will it take to receive "HRK Antibody - N-terminal region (ARP46364_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "HRK Antibody - N-terminal region (ARP46364_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    This target may also be called "DP5, HARAKIRI" in publications.

  5. What is the shipping cost for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "10kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "HRK Antibody - N-terminal region (ARP46364_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "HRK"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "HRK"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "HRK"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "HRK"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "HRK"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "HRK"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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