Catalog No: OPCD03966
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OPCD03966
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Datasheets/ManualsPrintable datasheet for HP Recombinant Protein (OPCD03966)
Product Info
Predicted Species ReactivityRat|Rattus norvegicus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationCtrl (+), SDS-PAGE, WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gly125-Gly297
::Subcellular Location: Secreted.
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolHp
Gene Full Namehaptoglobin
Alias SymbolsBa1-647;haptoglobin;liver regeneration-related protein LRRG173;zonulin.
NCBI Gene Id24464
Protein NameHaptoglobin
Description of TargetAs a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
Uniprot IDP06866
Protein Accession #NP_036714.2
Nucleotide Accession #NM_012582.2
Protein Size (# AA)Gly125~Gly297
Molecular Weight20kDa
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