- Gene Symbol:
- HP
- NCBI Gene Id:
- 3240
- Official Gene Full Name:
- Haptoglobin
- Protein Name:
- Haptoglobin
- Swissprot Id:
- P00738
- Protein Accession #:
- NP_005134
- Nucleotide Accession #:
- NM_005143
- Alias Symbols:
- hp2-alpha, BP, HPA1S, HP2ALPHA2
- Replacement Item:
- This antibody may replace item sc-134464 from Santa Cruz Biotechnology.
- Description of Target:
- Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
- Protein Size (# AA):
- 406
- Molecular Weight:
- 45kDa
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Purification:
- Affinity Purified
- Application:
- WB, IHC
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express HP.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express HP.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human HP
- Tested Species Reactivity:
- Human
- Predicted Homology Based on Immunogen Sequence:
- Dog: 77%; Guinea Pig: 77%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 92%; Rat: 92%
- Complete computational species homology data:
- Anti-HP (ARP42218_P050)
- Peptide Sequence:
- Synthetic peptide located within the following region: MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYVEHSVRY
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Protein Interactions:
- GADD45G; LAMC3; MVP; WASL; TP63; TGM2; TBL1X; RPL11; SMAD3; ALB; VKORC1; ATP7B; ELAVL1; RBBP6; GRB2; MIS12; C1RL; CD163; ADAMTS4; ITGB2; HBB; ITGAM; CD22;
- Blocking Peptide:
- For anti-HP (ARP42218_P050) antibody is Catalog # AAP42218 (Previous Catalog # AAPP24641)
- Datasheets/Manuals:
- Printable datasheet for anti-HP (ARP42218_P050) antibody
- Target Reference:
- Borsody,M., (2006) Neurology 66 (5), 634-640
Product Reviews
- Protocol:
- Tips Information:
See our General FAQ page.
