Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP31964_P050
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Conjugation Options

ARP31964_P050-FITC Conjugated

ARP31964_P050-HRP Conjugated

ARP31964_P050-Biotin Conjugated

HOXD3 Antibody - middle region (ARP31964_P050)

Catalog#: ARP31964_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species ReactivityHuman
Predicted Species ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-130378 from Santa Cruz Biotechnology.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human HOXD3
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Complete computational species homology dataAnti-HOXD3 (ARP31964_P050)
Peptide SequenceSynthetic peptide located within the following region: AHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPS
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-HOXD3 (ARP31964_P050) antibody is Catalog # AAP31964 (Previous Catalog # AAPP02861)
Datasheets/ManualsPrintable datasheet for anti-HOXD3 (ARP31964_P050) antibody
Publications

Kodama, A. et al. Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes. BMC Cancer 9, 363 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19825192

Kodama, A. et al. Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours. J. Comp. Pathol. 141, 199-203 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19505696

Gene SymbolHOXD3
Official Gene Full NameHomeobox D3
Alias SymbolsHOX1D, HOX4, HOX4A, Hox-4.1, MGC10470
NCBI Gene Id3232
Protein NameHomeobox protein Hox-D3
Description of TargetHOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
Swissprot IdP31249
Protein Accession #NP_008829
Nucleotide Accession #NM_006898
Protein Size (# AA)432
Molecular Weight46kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express HOXD3.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express HOXD3.
Protein InteractionsHoxa1; ALX4; DDB1; HMGB1;
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