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HOXD3 Antibody - middle region (ARP31964_P050)

100 ul
$319.00
In Stock
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Conjugation Options

ARP31964_P050-FITC Conjugated

ARP31964_P050-HRP Conjugated

ARP31964_P050-Biotin Conjugated

Gene Symbol:
HOXD3
Official Gene Full Name:
Homeobox D3
NCBI Gene Id:
3232
Protein Name:
Homeobox protein Hox-D3
Swissprot Id:
P31249
Protein Accession #:
NP_008829
Nucleotide Accession #:
NM_006898
Alias Symbols:
HOX1D, HOX4, HOX4A, Hox-4.1, MGC10470
Replacement Item:
This antibody may replace item sc-130378 from Santa Cruz Biotechnology.
Description of Target:
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
Protein Size (# AA):
432
Molecular Weight:
46kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express HOXD3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express HOXD3.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human HOXD3
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-HOXD3 (ARP31964_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
Hoxa1; ALX4; DDB1; HMGB1;
Blocking Peptide:
For anti-HOXD3 (ARP31964_P050) antibody is Catalog # AAP31964 (Previous Catalog # AAPP02861)
Datasheets/Manuals:
Printable datasheet for anti-HOXD3 (ARP31964_P050) antibody
Publications:

Kodama, A. et al. Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes. BMC Cancer 9, 363 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19825192

Kodama, A. et al. Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours. J. Comp. Pathol. 141, 199-203 (2009). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 19505696

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