HOXC11 Antibody - middle region (ARP32642_T100)

Catalog No: ARP32642_T100

WB Suggested Anti-HOXC11 Antibody Titration: 1.25ug/ml
Positive Control: Transfected 293T

Host: Rabbit
Target Name: HOXC11
Sample Tissue: Human RPMI 8226 Whole Cell
Antibody Dilution: 1ug/ml

Sample Type:
Mouse lumbar spinal cord sections
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit-Cy3
Secondary Antibody Dilution:
1:800
Color/Signal Descriptions:
Red: HOXC11
Gene Name:
HOXC11
Submitted by:
Anonymous

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC11
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: DRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEA
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-HOXC11 (ARP32642_T100) antibody is Catalog # AAP32642 (Previous Catalog # AAPP03652)
• Reference: Kosaki,K., (2002) Teratology 65 (2), 50-62

Target Info

• Gene Symbol: HOXC11
• Gene Full Name: Homeobox C11
• Alias Symbols: HOX3H
• NCBI Gene Id: 3227
• Protein Name: Homeobox protein Hox-C11
• Description of Target: HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
• Uniprot ID: O43248
• Protein Accession #: NP_055027
• Nucleotide Accession #: NM_014212
• Protein Size (# AA): 304
• Molecular Weight: 34kDa
• Protein Interactions: HTT; ELAVL1; CD2AP; SOX8; TBX21; GTF2A1L; HDAC5; STAT3; SP1; MEIS1; SMAD3; IRF4; GTF2H1;