HOXB3 Antibody - N-terminal region (ARP58020_P050)

Catalog No: ARP58020_P050

WB Suggested Anti-HOXB3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Liver

Host: Rabbit
Target Name: HOXB3
Sample Type: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml

WB Suggested Anti-HOXB3 antibody Titration: 1 ug/mL
Sample Type: Human liver

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: SCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGT
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-HOXB3 (ARP58020_P050) antibody is Catalog # AAP58020 (Previous Catalog # AAPP32443)

Target Info

• Reference: Speleman,F., (2005) Leukemia 19 (3), 358-366
• Gene Symbol: HOXB3
• Gene Full Name: Homeobox B3
• Alias Symbols: HOX2, HOX2G, Hox-2.7
• NCBI Gene Id: 3213
• Protein Name: Homeobox protein Hox-B3
• Description of Target: HOXB3 belongs to ANTP homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. HOXB3 gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P14651
• Protein Accession #: NP_002137
• Nucleotide Accession #: NM_002146
• Protein Size (# AA): 431
• Molecular Weight: 44kDa
• Protein Interactions: CREBBP; EP300; HMGB1;